Misiyano munzvimbo umo TFA munyu, acetate, uye hydrochloride inoshandiswa mu peptide synthesis.

Munguva yepeptide synthesis, imwe munyu inoda kuwedzerwa.Asi kune marudzi mazhinji emunyu, uye marudzi akasiyana emunyu anoita mapeptide akasiyana, uye mhedzisiro yacho haina kufanana.Saka nhasi isu tinonyanya kusarudza yakakodzera mhando yemunyu wepeptide mune peptide synthesis.

1. Trifluoroacetate (TFA) : Uyu munyu unowanzoshandiswa muzvigadzirwa zvepeptide, asi zvinoda kudziviswa mune zvimwe zvidzidzo nekuda kwebiotoxicity ye trifluoroacetate.Somuenzaniso, masero ekuedza.

2. Acetate (AC) : The biotoxicity yeacetic acid yakanyanya kudarika trifluoroacetic acid, saka peptides yakawanda yemishonga uye cosmetic inoshandisa acetate, asi zvimwe zvigadzirwa zvine acetate isina kugadzikana, saka kugadzikana kwekutevedzana kunodawo kufungwa.Acetate yakasarudzwa kune yakawanda masero ekuedza.

3. Hydrochloric acid (HCL) : Uyu munyu hauwanzosarudzwa, uye mamwe maitiro chete anoshandisa hydrochloric acid nokuda kwezvinangwa zvakakosha.

4. Ammonium munyu (NH4 +) : Uyu munyu uchakanganisa zvakanyanya kugadzikana uye kugadzikana kwechigadzirwa, inofanira kusarudzwa maererano.

5. Sodium munyu (NA +) : inowanzokonzera kugadzikana uye kunyungudika kwechigadzirwa.

6. Pamoicacid: Uyu munyu unowanzoshandiswa mumishonga yepeptide kuita maajenti anoramba achisunungurwa.

7. CitricAcid: Uyu munyu une zvishoma zvishoma zvehupfu hwemuviri, asi kugadzirira kwayo kwakaoma zvikuru, saka nzira yekugadzira inoda kugadzirwa sequentially uye zvakasiyana.

8. Salicylicacid: Salicylate inogona kukanganisa kugadzikana kwezvinhu zvepeptide, saka haiwanzoshandiswa.

Izvo zviri pamusoro apa marudzi akati wandei emunyu wepeptide, uye isu tinofanirawo kusarudza zvinoenderana nehunhu hwemunyu wakasiyana mukushandiswa chaiko.


Nguva yekutumira: Jun-16-2023