Peptide cheni synthesis yakashandiswa zvakanyanya mundima dzakawanda, kunyanya mukuvandudza zvinodhaka, biological research uye biotechnology.Mapeptide ehurefu hwakasiyana uye kutevedzana anogona kugadzirwa kuburikidza ne peptide cheni synthesis yekugadzirira zvinodhaka, mutakuri wezvinodhaka, kuongororwa kweprotein, tsvakiridzo inoshanda uye zvichingodaro.Saka chii chinotungamira chesynthetic peptides?Nhasi, Gutuo Xiaobian achakupa mhinduro yakadzama pazasi.
Ndeipi kutaridzika kwemapeptides akagadziridzwa akagadziridzwa?Unoziva pfungwa idzi here?
Peptide cheni synthesis inogona kuwanikwa nekuwedzerwa nhanho kweamino acid mamorekuru kune iripo peptide cheni, ichigadzira nyowani peptide zvisungo.Nekuda kwekukura kubva kuN end kusvika kuC peptide chain, saka kutungamira kweiyo synthesis kunobvawo kuN end kusvika kuC. Izvi zvinodaro nekuti C terminal uye N terminal amino acids pakati pepeptide bond formation process, iyo amino acids ye carboxyl end. (C) uye iripo amino (N) pakupera kwepeptide chain reaction, inokonzeresa nyowani peptide bond.Saka, kutungamira kwe synthesis kubva kuN kumagumo kusvika kuC.
Peptide synthesis inonyanya kubatanidza maamino acid mamorekuru kuburikidza nemakemikari nzira kuumba maitiro epeptides.Kuve yakananga, iyo polypeptide cheni synthesis inobatanidza amino acid mamorekuru, zvakare, anogona kuumbwa nemakemikari zvisungo kuvaka maitiro epeptides.Peptide cheni synthesis inogona kazhinji kuitiswa ingave yakasimba-chikamu synthesis kana liquid-phase synthesis.Mune solid-phase synthesis, yekutanga amino acids inonamirwa kune yakasimba-chikamu zvinhu, uye ipapo peptide cheni inowedzerwa sequentially nekuwedzera nhanho yemunhu amino acids.
Pamusoro pane diki kugadzira kuunza kupatsanurwa kwepeptide uye basa reruzivo rwakabatana, tinto yakasimba inotarisa peptide synthesis, protein kutaura, antibody kugadzirira, nezvimwewo, iri kuita peptide indasitiri kwemakore mazhinji, yekutanga-kirasi chigadzirwa mhando. , gamuchirai mhomho yevatengi kuti vauye kuzobvunza.
Nguva yekutumira: Zvita-08-2023