Mechanism ye tripeptide yehuturu hwenyoka

Uturu hwenyoka tripeptide

Analytical mwero, HPLC98%

Zita reChirungu: (2S) -beta-alanyl-l-prolyl-2, 4-Diamino-n -(phenylmethyl)butanamide acetate

Aliases: (2S) -beta-alanyl-l-prolyl 2, 4-diamino-n -(phenylmethyl) butyricoacetate;(2S) -beta-alanyl-l-prolyl-2, 4-Diamino-N -(phenylmethyl)butanamide acetate;SYN-AKE;nyoka-tripeptide;H – beta – Ala – Pro – Dab – NHBzl.2 acoh;Nyoka tr

Nhamba yeCAS: 823202-99-9

Molecular formula: C19H29N5O3.2(C2H4O2)

Molecular uremu: 495.58

Nhanganyaya:

Kutevedzana: H-β-Ala-Pro-Dab-NH-Bzl

Kuonekwa: White powder

Nhanganyaya pfupi:

Snake venom peptide inongova peptide diki inotevedzera muchetura wehuturu hwenyoka.Haisi uturu hwenyoka, asi chimiro chekuita polypeptide yakafanana nehuturu hwenyoka.Snake venom peptides aive akanyanya kushanda zvakapetwa kashanu pakudzikisa mitsara ine simba kupfuura Botox, uye mu vivo bvunzo dzakaratidza kuti mushure memazuva makumi maviri nemasere ekushandiswa vakave nemhedzisiro inoderedza mikwinya ne52%.

Kubudirira

1. Kuunyana uye anti-kuchembera

2. Bvisa maitiro eganda

3. Zvigadzirwa zvekuchengetedza zvega zvechiso, mutsipa nemaoko

4. Bvisa ganda reganda, ita kuti ganda rive jena, nyoro uye rakapfava, vandudza ruvara rwese

5. Inogona kupinda mukati meganda rakadzika rechiso, kuchengetedza ganda, uye kubvisa zvinyorwa zvakasara nemakore

6. Tamba zvinonyorovesa uye zvinonyorovesa, kuitira kuti ganda rive nyoro uye rakatsetseka, rakanaka sekare.

7. Kudhiraivha, kudzivirira kuchembera, kuratidza hydrating V-yakaita ovha kumeso, kuderedza ganda rechiso pwere.

8. Chengetedza ganda kubva pakugadzirwa kwe melanin

Mhedzisiro:

Iyo dipeptide diaminobutylbenzylamide diacetate/huturu-hwakaita tripeptide inogona kushandiswa sechigadzirwa kunyatso vandudza uye kubvisa kuunyana simba nekuzorodza mhasuru dzechiso.Basa retatu rinoita nenzira imwecheteyo seWaglerin1, iyo neuromuscle-blocking compound muTempleViper venom.Uturu hwenyoka-senge tripeptides inoshandiswa kune postsynaptic membrane uye inodzokororwa vashori ve muscular nicotinic acetylcholine receptor (nmAChR).Uturu hwenyoka tripeptide inosunga nmAChRεsubunit kudzivirira kusanganiswa kweacetylcholine uye kuzadzisa receptor, zvichiita kuti mubatsiri wekugamuchira akavharwa, mumamiriro akavharwa sodium ion haigoni kushandiswa, haigoni depolarization, nerve excitation transmission block, muscle relaxation.


Nguva yekutumira: May-06-2023