Custom PeptideSynthesisService
Hangzhou Enda Pamusoro Peptide Biotech , yakavambwa muna 2014, is a National High-tech Enterpriseinyanzvi mukutsvagisa, kusimudzira uye kugadzirwa kwepeptides uye zvine hukama zvinobva.
Iyo kambanipeptide research centreparizvino iri muQiantang Districtof Hangzhou, inofukidza nzvimbo inopfuura 3,000 square metres.Thekambani's factory iri paNo.24, Haitian Road, Shangyu District, Shaoxing city, Zhejiang province.Kune zvakare zvirimwa zviviri zvekubatana, imwe ndeyekutengeserana peptide GMP kugadzira iri muAnji County mudunhu reZhejiang, imwe ndeyediki molecule API iri mukatiYuncheng guta reShanxi mudunhu.Tinovabhizimusi repamusoro-soro, kubatanidza tsvakurudzo, pilot scale-up, kushambadzira uye kutengesa kwenyika yose.
Iyo kambani inepamusoro100vashandi,uye aneyakasimukira kupfuura40 mature pharmaceuticalpeptides,kupfuurisa10 ekugadzira patentsvakatenderwa.Tiye pagore kugadzirwa kugonais kusvika pa100 makirogiramu, nhamba yetsika peptides ine kusvika pamusoro pe20,000.Tinogona kupa iyo-yekumira peptide masevhisi kubva pakutsvagisa(mg) kuenda kukutengesa (KGs).
Peptide Modification List
N-terminal kugadzirisa
| {N-Me-Ala} | {N-Me-Asp} | {N-Me-Glu} | {N-Me-Ile} |
| {N-Me-Leu} | {N-Me-Met} | {N-Me-Nle} | {N-Me-Nva} |
| {N-Me-Phe} | {N-Me-Ser} | {N-Me-Thr} | {N-Me-Tyr} |
| {N-Me-Val} | {Sar} | N-Me-Arg | N-Me-Asn |
| N-Me-beta-Ala | N-Me-Gln | N-Me-Lys | N-Me-Trp |
C-terminal kugadzirisa
| {Mono Disulfide zambuko} | {Zambuko reDisulfide kaviri} | {Zambuko reTriple Disulfide} |
| {Random Disulfide zambuko} | {Same Seq.Inter-Disulfide zambuko } | {Dzambuko rakasiyana reInter-Disulfide} |
| {Amide cyclic (kupera)} | {Amide cyclic (Side cheni)} | {Orn side cheni Amide cyclic} |
| {Thioester cyclic} | {lactone cyclic} | {Sec cyclic} |
Zvisina kujairika amino acids
| {2-Aze} | {3-Aze} | {5,5-Dime-Pro} |
| {5-ASA} | {Abhu} | {Ac-Ls} |
| {Aib} | {Beta-Asp} | {Bpa} |
| {Cha} | {Chg} | {Cit} |
| {Cpg} | {Cs(Acm)} | {Cys(Bzl)} |
Isotope yakanyorwa peptides
| Lys(13C6,15N2) | Ile(13C6,15N) |
| Leu(13C6,15N) | Val(13C5, 15N) |
| Arg(13C6, 15N4) |
Fluorescent peptide shanduko/FRET pairs
| Biotin - | Dansyl- | Yakadzima fluorecent peptide |
| Biotin-Ahx- | Dansyl-Ahx- | Dabcyl |
| 5-FAM- | Cy3- | Dabcyl / Glu(Edans)-NH2 |
| 5-FAM-Ahx- | Cy5- | Dansyl- |
| FITC- | MCA/DNP | Dansyl-Ahx- |
| FITC-Ahx- | AMC | Edans / Dabcyl |
Peptide Conjugates
| BSA (-COOH yeC terminal | KLH(-NH2 yeN terminal) | OVA(-COOH yeC terminal) |
| BSA Conjugation paCys | KLH Conjugation paCys | OVA(-NH2 yeN chiteshi) |
| OVA Conjugation paCys |
Phosphorylation
| {pSer} | {D-pSer} |
| {pTyr} | {D-pTyr} |
| {pThr} | {D-pThr} |
Zvimwe zvigadziriso(PEGylation, Cyclic modifications,Disulfide Bridges)
| PEGylation | Cyclic shanduko | Disulfide Bridges |
| {Mini-PEG1} | Head to tail cyclic | {Mono Disulfide zambuko} |
| {Mini-PEG2} | {Zambuko reDisulfide kaviri} | |
| {PEG-11} | {Zambuko reTriple Disulfide} | |
| {PEG-12} | {Random Disulfide zambuko} | |
| ……… | ……… | ……… |